Mice Toxicity Study 2

The results generated during Phase I demonstrated high decontamination efficacy of Microaerosol of Electrochemically Activated Solution (MAEAS) toward a variety of bioagents, including G-positive and G–negative microbial cells, bacterial spores, and viruses. It was shown that the contact of different bioagents with MAEAS resulted in serious morphology damage and irreversible death of microbial cells, spores and viruses. First MAEAS toxicity study was conducted with outbred white mice to observe toxicity of MAEAS. As the controls, microaerosols generated with dist water and with 1% NaCl were used. Minor and very similar variations were found in liver, spleen and lungs of the animals exposed to MAEAS and to the aerosol of 1% NaCl. That indicated that MAEAS was not more toxic than the aerosol of 1%NaCl. This study of MAEAS toxicity was conducted in the conditions simulating MAEAS application for volumetric disinfection of enclosed environment.